NT Pro BNP (PBN)
Department: Special Chemistry
Test Synonym(s): LAB5778, PBN, N-terminal Pro B-type Natriuretic Peptide
Test Components: ProBNP
CPT Codes: 83880
Methodology: Electrochemiluminescence Immunoassay
Tube Type: Lavender top (EDTA)
Specimen: Blood
Pediatric Requirements: 1 lavender top microtainer
Volume: 1 mL plasma
Minimum Volume: 1 lavender top
Stability: Room temperature: 3 days; Refrigerated: 6 days; Frozen: 2 years
Reasons for Rejection: Hemoylsis, Icteric specimens, improper collection, QNS
Days Performed: Daily
Times Performed: Continuous
TAT: 2 hours after receiving in lab
Significance: Biotin Interference possible. Samples should not be taken from patients receiving therapy with high biotin doses (ie, >5 mg/day) until at least 8 hours following the last biotin administration.
Special Instructions: This test is intended only for patients on Entresto (Sacubitril). Patients not on Entresto should order BNP levels to monitor natriuretic peptides. NT ProBNP ref range is a cutoff of 300 pg/mL. European Heart Journal (2012) 33, 17871847. J Am Coll Cardiol 2013;62:e147239. European Journal of Heart Failure (2016) 18, 891-975.
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