MIDL Bacterial Vaginosis ()
Department: Molecular Infectious Disease
Test Synonym(s): LAB6082, BV, PCR, Wet Prep, Vaginosis
CPT Codes: 87801
Methodology: TMA
Reference Range: Negative
Tube Type: Aptima Multitest Swab Collection Kit
Specimen: Vaginal
Alternate Specimen: None
Temperature: 2 - 30 C
Stability: 30 days
Reasons for Rejection: Incorrect collection device, no swab present
Days Performed: Tuesday and Thursday
TAT: >72 hours
Significance: A positive test result does not necessarily indicate the presence of viable organisms. A positive result is indicative of the presence of target RNA. A positive result may by due to the presence of multiple organisms including Lactobacillus (L. gasseri, L. crispatus, and L. jensenii), Gardnerella vaginalis, and Atopobium vaginae. The assay reports a qualitative result for BV and does not report results for individual organisms.
Special Instructions: The Aptima collection kit is not acceptible for CT/NG testing, which requires a different collection kit. Please contact MIDL (615-936-6435) for additional information. The Aptima BV assay has not been evaluated for use with specimens collected by patients at home. Collection and testing of patient-collected vaginal swab specimens with the Aptima BV assay is not intended to replace clinical examination. Additional microorganisms not detected by the Aptima BV assay such as Prevotella species and Mobiluncus species, Ureaplasma, Mycoplasma, and numerous fastidious or uncultivated anaerobes have also been found in women with BV, but are less associated with BV due to their relatively low prevalence, sensitivity, and/or specificity. Cross-reactivity was observed with the Aptima BV assay in the presence of Lactobacillus acidophilus (1x10e4 CFU/mL).
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