Uric Acid w/Rasburicase ()
Department: Chemistry
Test Synonym(s): LAB6612, Uric Acid w/RAS, Uric Acid with Rasburicase
Test Components: Uric Acid
CPT Codes: 84550
Methodology: Uricase
Reference Range: 0-14 days: 2.8-12.7mg/dL; 15 days- <1 year: 1.6-6.3 mg/dL; 1 year- <12 Yead: 1.8-4.9 mg/dL; 12 years- <19 years: 2.6-7.6 mg/dL (male) 2.6-5.9 mg/dL (female); 19 years and older: 3.5-7.2 mg/dL (male) 2.6-6.0 mg/dL (female)
Tube Type: Light green top (Lithium Heparin)
Specimen: Plasma
Pediatric Requirements: 1 light green top microtainer
Volume: 1 Light green top
Minimum Volume: 2 mL Plasma
Temperature: Sample must be kept on ice
Stability: On Ice: 4 hours; ≤ -20C: 3 months
Reasons for Rejection: Sample not on ice, quantity not sufficient
Days Performed: Daily
Times Performed: Continuous
Significance: In patient who has tumor lysis syndrome, rasburicase may be used to manage the elevation of uric acid.Keeping the specimen cold will prevent breakdown of uric acid by rasburucase ex vivo. This allows for more accurate measurement of the uric acid level in vivo.
Special Instructions: If the patient is not on rasburicase, please order Uric Acid (LAB141).
Centrifuge (cold, if possible) to separate immediately.Place Centrifuged specimen on ice and assay immediately.
For off-campus labs or non-testing performing sites: centrifuge, remove plasma, and freeze plasma immediately. Testing sites must perform testing as soon as frozen plasma is thawed. Thoroughly mix thawed plasma prior to testing.
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