Lupus Anticoag DRVVT (RVV)
Department: Coagulation
Test Synonym(s): LAB3447, RVV, DRVVT, Lupus Anticoagulant DRVVT
CPT Codes: 85613
Methodology: Clotting
Reference Range: Ratio 0.7 - 1.2
Tube Type: One 2.7mL Light blue top - 3.2% Sodium Citrate
Specimen: Citrated platelet poor plasma - Requires double centrifugation if sending a plasma aliquot. Aliquot(s) must be frozen if not received by lab within 4 hours of collection.
Alternate Specimen: None
Pediatric Requirements: Pediatric: One 2.7mL Light blue top - 3.2% Sodium Citrate. Neonatal: One 1.8mL Light blue top - 3.2% Sodium Citrate.
Volume: 1.0 mL plasma
Minimum Volume: 1.0 mL plasma
Temperature: Room Temperature for Light blue top tube, must be received within 4 hours of draw. Plasma aliquot(s) must be frozen if not received by lab within 4 hours of collection.
Stability: Room temperature: 4 hours, Frozen: -70 C for one month
Reasons for Rejection: Clotted sample, incorrectly filled tubes, incorrect tube type, grossly hemolyzed sample, grossly lipemic sample, grossly icteric sample, whole blood >4.0 hours old
Days Performed: Monday - Friday
Times Performed: Twice weekly
TAT: 1 - 3 days
Significance: A positive test (ratio > 1.2) will generate reflex testing for confirmation. High doses of Heparin can interfere with this assay. Direct Thrombin and both direct and indirect Xa inhibitors may interfere with this assay. Factor VIII levels > 200% may interfere with the assay.
Special Instructions: This test on its own is not adequate for the evaluation of the Antiphospholipid Antibody Syndrome. A more appropriate test for work up of Antiphospholipid Antibody Syndrome is the Antiphospholipid Ab Pnl [LAB2307]. Performed twice weekly. Collect partial waste tube if using butterfly device. Do not send on ice. Deliver to lab immediately.
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