Prekallikrein Scrn (PRE)
Department: Coagulation
Test Synonym(s): LAB1114, PRE
CPT Codes: 85292
Methodology: Clotting
Reference Range: Screen reveals no evidence of HMWK or prekallikrein deficiency.
Tube Type: Light blue top (Sodium Citrate) - 2 tubes required
Specimen: Citrated platelet poor plasma - Requires double centrifugation if sending a plasma aliquot. Aliquot(s) must be frozen if not received by lab within 4 hours of collection.
Alternate Specimen: None
Pediatric Requirements: Pediatric: One 2.7mL Light blue top - 3.2% Sodium Citrate. Neonatal: One 1.8mL Light blue top - 3.2% Sodium Citrate.
Volume: Plasma from 2 (2.7 mL) light blue (Sodium Citrate) tubes
Minimum Volume: Plasma from 2 (2.7 mL) light blue (Sodium Citrate) tubes
Temperature: Room Temperature for Light blue top tube, must be received within 4 hours of draw. Plasma aliquot(s) must be frozen if not received by lab within 4 hours of collection.
Stability: Room temperature: 4 hours, Frozen: -70 C for one month
Reasons for Rejection: Clotted sample, incorrectly filled tubes, incorrect tube type, grossly hemolyzed sample, grossly lipemic sample, grossly icteric sample, whole blood >4.0 hours old
Days Performed: Monday - Friday
Times Performed: 8:00 a.m. - 3:00 p.m. After hours testing must be approved by the Director or Pathology resident on call.
TAT: 1 day
Significance: Direct Thrombin and both Direct and Indirect anti-Xa inhibitors may interfere with these assays.
Special Instructions: Indwelling line should be flushed with saline and 5.0 mL of blood discarded before collecting samples for coagulation assays. Tube must be full and not clotted. Deliver to lab immediately. Samples received from an outside lab must be aliquoted and frozen. Samples aliquoted for shipping must be double centrifuged prior to freezing. Grossly hemolyzed, icteric or lipemic samples may be rejected.
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