Direct Renin/Renin Mass (DRM)

Department: Special Chemistry
Test Synonym(s): LAB5712, Renin, Plasma Renin, Direct Renin, Renin Mass
Test Components: Direct Renin/Renin Mass
CPT Codes: 84244
Methodology: Chemiluminescent Immunoassay
Reference Range: Upright: 2.5-45.7 pg/mL
Tube Type: Lavender top (EDTA)
Specimen: Blood
Right Click here to view Sample Collection Instructions.
Alternate Specimen: None
Pediatric Requirements: 2 lavender top microtainers
Volume: 4 mL
Minimum Volume: 1 lavender top (Pediatric = 2 lavender top microtainers)
Temperature: Room temperature
Stability: Plasma stable 72 hours at room temp or 56 days frozen (-20 C)
Reasons for Rejection: Refrigeration of sample
Days Performed: Tuesday and Friday
Times Performed: 8:00 a.m. - 2:00 p.m.
TAT: 5 days
Significance: Primarily used in conjunction with aldosterone as a screen for primary hyperaldosteronism (aldosterone/renin mass ratio).
Right Click here to view Aldosterone/Renin Interference Table.
Right Click here to view Direct Renin/Renin Mass Comparison to Plasma Renin Activity.
Special Instructions: Do not refrigerate samples during collection, transport, or storage. Collect, process, and centrifuge at room temperature.

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