MDL Factor V-R506Q DNA Mut Anly (FVM)
Department: Molecular Diagnostics
Test Synonym(s): LAB3030, FVM, Factor V Leiden Mutation, R506Q DNA Mutation Analysis, Factor V Gene
CPT Codes: 81241
Methodology: Direct Detection of Variant c.1601G>A (p.R506Q) by using predesigned Taqman SNP Genotyping assay for c.1601G>A (p.R506Q); Laboratory Developed Test
Tube Type: Lavender top (EDTA)
Specimen: Whole blood
Alternate Specimen: Light blue top (Sodium Citrate)
Pediatric Requirements: 2 microtainers
Volume: 1 tube
Minimum Volume: 2 microtainers blood
Temperature: EDTA: room temperature or refrigerated; purified DNA: refrigerate or freeze
Stability: EDTA - Room temperature: 2 days Refrigerated: 7 days; Purified DNA - indefinitely @ -70C
Reasons for Rejection: Client will be notified by Molecular Diagnostics Lab if specimen is rejected. Purified DNA - externally extracted nucleic acid received for clinical testing only accepted from CLIA-certified laboratories or laboratories meeting equivalent requirements as determined by College of American Pathologists (CAP) and/ or CMS. Documentation stating that the DNA was extracted in a CLIA lab will be required and should accompany the DNA specimen. DNA samples received from facilities not meeting requirement will be rejected. The Molecular Diagnostic Laboratory medical director will contact the referral facility.
Days Performed: Once per week - variable days
Times Performed: Batched
TAT: 10 days
Significance: Direct Detection of Variant R506Q
Special Instructions: Call or email the Molecular Diagnostics Laboratory at 615-343-8121 or moleculardiagnosticlab@vumc.org if assistance is needed for specimen submission or if the patient has received a transfusion in the prior 2 weeks or has a history of a stem cell transplant.
Click here to print the Molecular Diagnostics requisition.
Search Help
Search Options for the Test Directory:
1. Enter the test name in the Keyword search field.
Hint: You can also enter any part of the test name to expand the search.
(Example: you can type "west" or "sed" or "rate" to find Westergren Sedimentation Rate)
2. Enter the Vanderbilt Test Code, if known.
3. Choose one of the letter boxes to display a list of all test names and keywords starting with that letter.
If you are unable to find a test in our directory, please contact VPLS at
1-800-551-5227 or e-mail emily.k.thompson@vumc.org.