Fetal Fibronectin (FFN)
Department: Chemistry
Test Synonym(s): LAB287, FFN
CPT Codes: 82731
Reference Range: Negative
Tube Type: Specimen should be cervicovaginal secretions obtained under sterile speculum conditions using the ADEZA Specimen Collection Kit. No other sample collection method is acceptable for this assay.
Specimen: Cervicovaginal secretions
Volume: 200 uL of sample
Minimum Volume: 200uL of sample
Temperature: Room temperature
Stability: Room temperature: 8 hrs; Refrigerated: 3 days; Frozen: 3 months
Reasons for Rejection: Frozen specimen. Not in Adeza Collection Kit.
Days Performed: Daily
Times Performed: STAT testing is available
Significance: Presence of fetal fibronectin (ffN) in symptomatic women indicates an increased risk for preterm delivery; absence of ffN in symptomatic women indicates decreased intervention. Utilization of ffN testing in symptomatic women may greatly reduce costs associated with treatment of suspected preterm labor. This test has been recommended by the American College of Obstetricians and Gynecologists (ACOG), who currently supports ffN testing as an adjunctive diagnostic tool in symptomatic patients. ffN testing has a positive predictive value of 40-60% and a negative predictive value of 99.5%.
Special Instructions: Collection kits are available from the laboratory. Douches, white blood cells, red blood cells, bacteria, and bilirubin may cause test interference. Transport 2 degrees Celsius - 25 degress Celsius, or frozen.
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